Heliotropium indicum L: An Ethnomedicinally Important plant of India

/ Uncategorized / By

Rupam Mandal
Department of Botany, Sree Chaitanya College, Habra, West Bengal, India.
OrchideID Icon https://orcid.org/0000-0002-0037-3726

DOI: https://doi.org/10.52756/bhietm.2022.e01.003

Keywords: Ethnomedicinally Important, Heliotropium indicum, phytopharmacological activities, Medicinal Value.

Abstract:
This study attempted to summarise the existing data on the ethnomedicinal and phytopharmacological activities of Heliotropium indicum L., and it did so by using database reports as its primary source of information. In order to accomplish this goal, a search of the most recent relevant literature was carried out. Based on the data, it appears that the plant possesses a significant quantity of essential phytochemicals. In the plant family known as the Boraginaceae, Heliotropium is a sizable genus that spans both the tropical and temperate regions of the world. Because most of the alkaloids that can be isolated from Heliotropium indicum are toxic, this plant’s use in treating internal conditions is not suggested. In order to provide light on potential directions for future research, the purpose of this review is to summarise the phytochemistry and pharmacological activity of the many species of Heliotropium.

References:

  • Adjanohoun, E. (2014) Le processus de r´enovation de la pharmacop´eeafricaine, Bulletin de la Soci´et´eBotanique de France Actualit´es Botaniques. 136(3-4): 35–39.
  • Ainslie, J. R. (1981) Fe List of Plants Used in Native Medicine in Nigeria, Imp, Forest Inst Oxford Inst Paper. vol. 7.
  • Akhter, J., Khatun, R. and Akter. S. (2021) Ethnomedicinal practices in Natore district, Bangladesh,World Journal of Pharmacy and Pharmaceutical Sciences, 5(8): 212–222
  • Alagesaboopathi, C. (2009) Ethnomedicinal plants and their utilization by villagers in Kumaragiri hills of Salem district of Tamilnadu, India. African Journal of Traditional, Complementary and Alternative Medicines. 6 (3): 222–227.
  • Andhiwal, C. K., Has, C., and Varshney, R. P., (2013) Chemical and pharmacological studies of Heliotropiumindicum. Indian Drugs. 22(11): 567–569.
  • Asprey, G. F., and ornton, P. (1955) Medicinal plants of Jamaica. Parts III. West Indian Medical Journal. 4(4) : 69–82.
  • Ayensu, E. S. (1981) Medicinal Plants of the West Indies, Reference Publications, Inc, Algonac, MI, USA
  • Banerjee, J., Biswas, S., Madhu, N. R., Karmakar, S. Re., & Biswas, S. J. (2014). A better understanding of pharmacological activities and uses of phytochemicals of Lycopodium clavatum: A review. Journal of Pharmacognosy and Phytochemistry. 3 (1): 207-210.
  • Bhattacharjee, P. (2021). Some medicinal plants with anti-fertility potential used by the tribal people of the District Cooch Behar, West Bengal, India. International Journal of Experimental Research and Review. 24: 30-39. doi: https://doi.org/10.52756/ijerr.2016.v03.006
  • Bhattacharjee, P., & Manna, C. K. (2016). Potential plants as nervine for Unani system of medicine from the Coochbehar district, West Bengal, India. International Journal of Experimental Research and Review. 5: 19-24.
  • Birecka, H., DiNolfo, T. E., Martin, W. B., and Frohlich, M. W. (1984) Polyamines and leaf senescence in pyrrolizidine alkaloidbearingHeliotropiumplants. Phytochemistry. 23(5): 991–997
  • Chakraborty, D., Das, D., Samal, A. C., and Santra, S. C. (2019). Prevalence and Ecotoxicological significance of heavy metals in sediments of lower stretches of the Hooghly estuary, India. International Journal of Experimental Research and Review. 19: 1-17. doi: https://doi.org/10.52756/ijerr.2019.v19.001
  • Coe F. G., and Anderson, G. J. (1996) Ethnobotany of the gar´ıfuna of Eastern Nicaragua, Economic Botany. 50 (1) : 71–107
  • Das, A. K., Dutta, B. K., and Sharma, G. D. (2008) Medicinal plants used by different tribes of Cachar district, Assam. Indian Journal of Traditional Knowledge. 7 (3): 446–454.
  • Dash, G. K., and Abdullah, M. S. (2012) A review on Heliotropiumindicum L. (Boraginaceae). International Journal of Pharmaceutical Sciences and Research. 4(4): 1253
  • Duke, J. A. (1994) Amazonia Ethnobotanical Dictionary, CRC Press, Boca Raton, FL, USA.
  • Erfani, H. (2021). The practical and potential importance of herbs such as ginger in Chemical Environmental Science. International Journal of Experimental Research and Review. 24:24-29. doi: https://doi.org/10.52756/ijerr.2021.v24.003
  • Goyal, N., and Sharma , S. (2014) Bioactive phytoconstituents and plant extracts from genus Heliotropium . InternationalJournal of Green Pharmacy. 8(4): 217–22
  • Kar, D., Ghosh, P., Suresh, P., Chandra, S., and Paul, D. (2022). Review on Phyto-chemistry & pharmacological activity of Melia azedarach. International Journal of Experimental Research and Review. 28: 38-46. https://doi.org/10.52756/ijerr.2022.v28.006
  • Kerharo, J., and Adam, J. G. (1974) La pharmacopees ´ en´egalaise ´ traditionnelle: plantesm´edicinalesettoxiques, Editions VigotFr`eres, vol. 1011.
  • Komlaga, G., Agyare, C., Dickson R. A., Annan, K, Loiseau, P.M., and Champy, P. (2015) Medicinal plants and finished marketed herbal products used in the treatment of malaria in the Ashanti region, Ghana. Journal of Ethnopharmacology. 172: 333–346.
  • Kundu, K. (2022). Management of root-knot nematodes, Meloidogyne incognita in Okra using wheat flour as bionematocides. International Journal of Experimental Research and Review. 28: 8-14. doi: https://doi.org/10.52756/ijerr.2022.v28.002
  • Kyei, S., Koffuor, G. A., Ramkissoon, P., Afari, C., and Asiamah, E. A. (2015) claim of anti-cataract potential of Heliotropiumindicum: a myth or reality? Ophthalmology and Ferapy. 4(2): 115–128.
  • Kyei, S., Koffuor, G. A., Ramkissoon, P., Ameyaw, E. O., and Asiamah, E. A. (2016) Anti-inflammatory effect of Heliotropiumindicum Linn on lipopolysaccharide-induced uveitis in New Zealand white rabbits. International Journal of Ophthalmology. 9(4): 528–535
  • Lin, C. C., and Kan, W. S. (1990) Medicinal plants used for the treatment of hepatitis in Taiwan. American Journal of Chinese Medicine. 181(1-2): 35–43.
  • Machan, T., Korth, J., Liawruangrath, B., Liaewruangrath, S., and Pyne, S. (2005) Composition and antituberculosis activity of the volatile oil of Heliotropiumindicum Linn. growing in Phitsanulok, ailand. Flavour and Fragrance Journal. 21(2) : 265–267.
  • Mahato, K., Kakoti, B. B., Borah, S., and Kumar, M. (2014) Evaluation of in-vitro anthelmintic activity of HeliotropiumindicumLinn. leaves in Indian adult earthworm. AsianPacific Journal of Tropical Disease. 4: S259–S262.
  • Maiti, A., Madhu, N. R. and Manna, C. K. (2013). Natural products traditionally used by the tribal people of the Purulia district, West Bengal, India for the abortifacient purpose. International Journal of Traditional Medicine (TANG). 3(2): e14. doi: http://dx.doi.org/10.5667/tang.2012.0045
  • Maiti, A., Madhu, N.R. and Manna, C. K. (2010). Ethnomedicine used by the tribal people of the district Purulia, W. B., India in controlling fertility : and experimental study. Pharmacologyonline. 1: 783-802.
  • Muthu, C., Ayyanar, M., Raja, N., and Ignacimuthu S. (2006) Medicinal plants used by traditional healers in Kancheepuram district of Tamil Nadu, India. Journal of Ethnobiology and Ethnomedicine. 2: 43.
  • Nawaz, A. H., Hossain, M., Karim, M., Khan, M., Jahan, R., and Rahmatullah, M. (2009) An ethnobotanical survey of Rajshahi district in Rajshahi division, Bangladesh, American-Eurasian Journal of Sustainable Agriculture. 3(2): 143–150.
  • Ohnuma, T., Sridhar, K. S., Ratner, L. H., and Holland, J. F., (1982) Phase I study of indicine N-oxide in patients with advanced cancer. Cancer Treatment Reviews. 66(7): 1509–1515.
  • Oluwatoyin, S., Ndukwe, G. I., and Joseph, A. (2011) Phytochemical and antimicrobial studies on the aerial parts of Heliotropiumindicum Linn. Annals of Biological Research. 2 (2): 129–136.
  • Osungunna, M. O., and Adedeji, K. A. (2016) Phytochemical and antimicrobial screening of methanol extract of Heliotropiumindicum leaf. Journal of Microbiology and Antimicrobials. 3 (8): 213–216.
  • Pandey, D. P., Singh, J. P., Roy, R., Singh, V. P., and Pandey, V. B. (1996) Constituents of Heliotropiumindicum, Oriental Journal of Chemistry. 12: 321-322.
  • Pianowski, L. F., Calixto, J. B., and Chaves, C. P. (2011) Pharmaceutical Oral Product Obtained from Parts of Heliotropium Plants. Patent no. WO2011086422A1
  • Quisumbing, E. (1951)Medicinal plants of the Philippines, Tech Bull, vol. 16, Pp. 126.
  • Rahman, M. A., Mia, M., and Shahid, I. (2011) Pharmacological and phytochemical screen activities of roots of Heliotropium indicum Linn. Pharmacology OnLine. 1(1): 185–192
  • Rao, P. R., Nammi, S., and Raju, A. D. V. (2002) Studies on the antimicrobial activity of HeliotropiumindicumLinn. Journal of Natural Remedies. 2(2): 195–198.
  • Reddy, J. S., Rao, P. R., and Reddy, M. S. (2002) Wound healing effects of Heliotropiumindicum, Plumbagozeylanicum and Acalyphaindicain rats. Journal of Ethnopharmacology. 79(2): 249–251
  • Sarkar, B. (2016). Ethnic practices and human welfare in India: An attempt for controlling fertility. International Journal of Experimental Research and Review. 2: 28-31. doi: https://doi.org/1 Bhattacharjee 0.52756/ijerr.2016.v2.006
  • Sarkar, B. (2017). Traditional use of medicinal plants and its biodiversity in India. International Journal of Experimental Research and Review. 10: 23-26.
  • Sanyal, R., Bala, S. and Mazumdar, A. (2016). Indigenous knowledge of Ethnic community on usage of Satavari (Asparagus racemosus Willd) and its preliminary screening. International Journal of Experimental Research and Review. 7: 62-68.
  • Sanyal, R., Mallick, S., and Mazumder, A. (2018). Indigenous Knowledge of Ethnic Community on Usage of Kripa (Lumnitzera racemosa) and its preliminary screening. International Journal of Experimental Research and Review. 15: 44-50. doi: https://doi.org/10.52756/ijerr.2018.v15.007
  • Savadi, R. V., Alagawadi, K. R. and Darade, S. S. (2009) Antifertility activity of ethanolic extract and its n-hexane and benzene fractions of Heliotropiumindicumleaves on albino rats. Journal of Pharmacy Research. 2 (5) : 927–930.
  • Shahnaj, S., Asha, U., Mim, T., Rumi, N.S.H., Akter, S., Ghose, S.R., Akter,S., Islam, M.T., Das, P.R., and Rahmatullah, M.(2015). A survey on the ethnomedicinal practices of a folk medicinal practitioner in Manikganj district, Bangladesh. Journal of Chemical and Pharmaceutical Research. 7 (8):690–696
  • Shalini, S., Kaza, R., and Shaik F. (2010) Study on the anti-inflammatory activity of Heliotropiumindicum. Journal of Innovative Trends in Pharmaceutical Sciences. 1(1): 43.
  • Souza, J. S. N., Machado, L. L., Pessoa O. D. L., Filho, R. B., Overk, C.R., Yao, P., Cordell, G.A., and Lemos, T.L.G. (2005) Pyrrolizidine alkaloids from Heliotropiumindicum. Journal ofthe Brazilian Chemical Society. 16(6B): 1410–1414.
  • Srinivas, K., Rao, M. E. B., and Rao, S. (2000) Anti-inflammatory activity of Heliotropiumindicum Linn and Leucasaspera Spreng. in albino rats. Indian Journal of Pharmacology. 32(1) :37-38
  • Suroowan, S., Pynee, K. B., and Mahomoodally, M. F., (2019) A comprehensive review of ethnopharmacologically important medicinal plant species from Mauritius. South African Journal of Botany. 122: 189–213.
  • Togola, A., Diallo, D., Demb´el´e, S., Barsett, H., and Paulsen, B. S. (2005) Ethnopharmacological survey of different uses of seven medicinal plants from Mali, (West Africa) in the regions Doila, Kolokani and Siby. Journal of Ethnobiology and Ethnomedicine. 1: 7.
  • Veda, V. T., Sasi, K. S., Asokan, B. R., Sengottuvelu, S., and Jaikumar, S. (2016) Anticataract activity of ethanolic extract of Heliotropiumindicumleaves on galactose induced cataract in rats. International Journal of Pharmacology & Toxicology. 5: 18–20
  • Wiart, C. (2006) Medicinal Plants of the Asia-Pacific, CRC Press, Boca Raton, FL, USA. Williaman J. J., and Schubert, B. G. (1962) Alkaloid-bearing plants and their contained alkaloids. Technical Bulletin No. 1234. Journal of Pharmaceutical Sciences. 51(3): 296.
Get PDF
The Basic Handbook of Indian Ethnobotany and Traditional Medicine Vol. 1 Cover
The Basic Handbook of Indian Ethnobotany and Traditional Medicine Vol. 1

How to Cite:
Rupam Mandal (2022). Heliotropium indicum L: An Ethnomedicinally Important plant of India. © International Academic Publishing House (IAPH), B. Sarkar (eds.), The Basic Handbook of Indian Ethnobotany and Traditional Medicine,Vol. 1, pp. 36-45.
https://doi.org/10.52756/bhietm.2022.e01.003